A Simple Twist of Fate 1994
Nancy Lambert Newland
106 mins.
Absolute Power 1997
Kate Whitney
121 mins.
Aimee Mann: Charmer 2012
Robot Aimee Mann
4 mins.
American Dad! 2005
Doctor Gupta
22 mins.
American Experience 1988
Narrator
60 mins.
American Masters 1985
Zelda Fitzgerald
90 mins.
Armistead Maupin's More Tales of the City 1998
Mary Ann Singleton
330 mins.
Armistead Maupin's Tales of the City 1993
Mary Ann Singleton
360 mins.
Arthur Christmas 2011
North Pole Computer
97 mins.
Assassins: A Film Concerning Rimbaud 1985
Extra
43 mins.
Biography 1987
Herself
60 mins.
Blind Spot 1993
Phoebe
120 mins.
Breach 2007
Kate Burroughs
110 mins.
Breakfast 2000
Herself - Guest
180 mins.
Class of '61 1993
Lily Magraw
95 mins.
Congo 1995
Dr. Karen Ross
109 mins.
Dave 1993
Randi
110 mins.
Day by Day: A Director's Journey Part I 2003
Herself
30 mins.
Driving Lessons 2006
Laura
98 mins.
E! Live from the Red Carpet 1995
Herself
240 mins.
Entertainment Tonight 1981
Herself
30 mins.
Frasier 1993
Charlotte
22 mins.
Frasier: Analyzing the Laughter 2004
Charlotte
60 mins.
Further Tales of the City 2001
Mary Ann Singleton
180 mins.
Genius 2016
Louise Perkins
104 mins.
Hyde Park on Hudson 2012
Daisy
94 mins.
Inside Amy Schumer 2013
Laura Linney
22 mins.
Inside the Actors Studio 1994
Herself - Guest
65 mins.
Jimmy Kimmel Live! 2003
Herself - Guest
60 mins.
Jindabyne 2006
Claire
123 mins.
John Adams 2008
Abigail Adams
71 mins.
King of the Hill 1997
Marlene
30 mins.
Kinsey 2004
Clara McMillen
118 mins.
Late Night with Conan O'Brien 1993
Herself - Guest
60 mins.
Late Night with Jimmy Fallon 2009
Herself - Guest
60 mins.
Late Show with David Letterman 1993
Herself - Guest
60 mins.
Law & Order 1990
Martha Bowen
45 mins.
Live! with Kelly 1988
Herself - Guest
60 mins.
Lorenzo's Oil 1992
Young Teacher
129 mins.
Love Actually 2003
Sarah
135 mins.
Love Letters 1999
Melissa Gardner Cobb
100 mins.
Lush 1999
Rachel Van Dyke
93 mins.
Man of the Year 2006
Eleanor Green
115 mins.
Masterpiece Classic 1971
Herself - Host
Maze 2000
Callie
97 mins.
Morning 2010
Doctor Goodman
95 mins.
Mr. Holmes 2015
Mrs. Munro
104 mins.
Mystic River 2003
Annabeth Markum
138 mins.
Nocturnal Animals 2016
Anne Sutton
116 mins.
Ozark
Wendy Byrde
P.S. 2004
Louise Harrington
97 mins.
Primal Fear 1996
Janet Venable
129 mins.
Running Mates 2000
Lauren Hartman
90 mins.
Searching for Bobby Fischer 1993
School Teacher
109 mins.
Speechless 2008
Herself
Sully 2016
Lorraine Sullenberger
96 mins.
Sympathy for Delicious 2010
Nina Hogue
96 mins.
Teenage Mutant Ninja Turtles: Out of the Shadows 2016
Chief Vincent
112 mins.
The Big C 2010
Cathy Jamison
30 mins.
The Broadway.com Show 2013
Herself
The City of Your Final Destination 2009
Caroline
117 mins.
The Daily Show 1996
Herself - Guest
22 mins.
The Details 2011
Lila
101 mins.
The Dinner 2017
Claire Lohman
The Exorcism of Emily Rose 2005
Erin Bruner
119 mins.
The Fifth Estate 2013
Sarah Shaw
128 mins.
The Hottest State 2006
Jesse
117 mins.
The House of Mirth 2000
Bertha Dorset
135 mins.
The Laramie Project 2002
Sherry Johnson
97 mins.
The Late Late Show with Craig Ferguson 2005
Herself - Guest
40 mins.
The Late Show with Stephen Colbert 2015
Herself
62 mins.
The Life of David Gale 2003
Constance Harraway
130 mins.
The Megan Mullally Show 2006
Herself - Guest
The Mothman Prophecies 2002
Connie Mills
119 mins.
The Nanny Diaries 2007
Mrs. X
105 mins.
The Other Man 2008
Lisa
88 mins.
The Savages 2007
Wendy Savage
113 mins.
The Squid and the Whale 2005
Joan Berkman
81 mins.
The Truman Show 1998
Meryl Burbank
103 mins.
The View 1997
Herself - Guest
60 mins.
Wild Iris 2001
Iris Bravard
93 mins.
You Can Count on Me 2000
Samantha 'Sammy' Prescott
111 mins.